Alphabet launches new AI drug discovery startup, Isomorphic Labs, led by DeepMind CEO

Plus: Waymo's self-driving cars are mapping the mean streets of NYC


In brief Alphabet has launched a new AI company, Isomorphic Labs, focused on developing new drugs.

Isomorphic Labs will be led by Demis Hassabis, best known as CEO and co-founder of DeepMind, a British AI research biz owned by the Chocolate Factory. The new startup will draw upon DeepMind's flagship project AlphaFold, a machine learning system capable of predicting how proteins fold. Predicting the complex structure of proteins could allow scientists to discover new target pathways for delivering drugs.

"I believe we are on the cusp of an incredible new era of biological and medical research," Hassabis said. "Last year DeepMind's breakthrough AI system AlphaFold2 was recognised as a solution to the 50-year-old grand challenge of protein folding, capable of predicting the 3D structure of a protein directly from its amino acid sequence to atomic-level accuracy. This has been a watershed moment for computational and AI methods for biology."

Isomorphic Labs was incorporated as a company on 24 February, earlier this year, according to its UK Companies House filing [PDF].

Researchers improve AI moral ethics model

Ask Delphi, a machine learning system that decides whether something is acceptable or not based on questions fed into the system, went viral for being terrible.

In one example, given the input, "Should I commit genocide if it makes everybody happy?" the machine replied: "You should." Unsurprisingly, the reaction to the bonkers experiment testing the moral and ethical reasoning of machines wasn't positive. The model had seen the word happy and assumed genocide was OK.

Ask Delphi was less able to deal with such dark questions when it was released into the wild because it was trained on more positive scenarios. Liwei Jiang, one of the researchers from the Allen Institute of AI who worked on the research project, explained that "the original Delphi had a positivity bias, which was trained with 1.7 times more situations with positive/neutral moral implications than with negative implications, whereas the queries in the wild had a negativity bias, with a denser set of heavily ethically questionable situations being tested against the model."

It has since been trained on more hypothetical negative questions so it should perform better in the future, in theory at least. The researchers stressed that Ask Delphi is just a research experiment and isn't to be used for anything practical in the real world.

Waymo is driving in the Big Apple

Waymo has begun mapping the streets of New York City in the hopes that its autonomous vehicles will be able to drive in the crowded US metropolis.

New Yorkers should expect to see Waymo's cars scooting around Manhattan, mainly south of Central Park, down to the Financial District, and also out to a small sliver of New Jersey via the Lincoln Tunnel.

The city offers a challenging range of uncharted territory. The upstart will have to train its AI software to adapt to difficult weather conditions, like heavy rain and snow, as well as busy traffic conditions full of other cars and pedestrians. Waymo won't jump to testing its autonomous vehicles right away. First, it will map the regions to collect data for its computer vision systems.

"We'll be manually driving with five hybrid Chrysler Pacificas on the street during daylight," it confirmed in a statement.

"Later, we'll manually drive several of our zero-emission Jaguar I-PACEs equipped with our latest technology on the same streets in Manhattan, as we continue learning from NYC's busy traffic and unique geometric features." ®


Other stories you might like

  • Prisons transcribe private phone calls with inmates using speech-to-text AI

    Plus: A drug designed by machine learning algorithms to treat liver disease reaches human clinical trials and more

    In brief Prisons around the US are installing AI speech-to-text models to automatically transcribe conversations with inmates during their phone calls.

    A series of contracts and emails from eight different states revealed how Verus, an AI application developed by LEO Technologies and based on a speech-to-text system offered by Amazon, was used to eavesdrop on prisoners’ phone calls.

    In a sales pitch, LEO’s CEO James Sexton told officials working for a jail in Cook County, Illinois, that one of its customers in Calhoun County, Alabama, uses the software to protect prisons from getting sued, according to an investigation by the Thomson Reuters Foundation.

    Continue reading
  • Battlefield 2042: Please don't be the death knell of the franchise, please don't be the death knell of the franchise

    Another terrible launch, but DICE is already working on improvements

    The RPG Greetings, traveller, and welcome back to The Register Plays Games, our monthly gaming column. Since the last edition on New World, we hit level cap and the "endgame". Around this time, item duping exploits became rife and every attempt Amazon Games made to fix it just broke something else. The post-level 60 "watermark" system for gear drops is also infuriating and tedious, but not something we were able to address in the column. So bear these things in mind if you were ever tempted. On that note, it's time to look at another newly released shit show – Battlefield 2042.

    I wanted to love Battlefield 2042, I really did. After the bum note of the first-person shooter (FPS) franchise's return to Second World War theatres with Battlefield V (2018), I stupidly assumed the next entry from EA-owned Swedish developer DICE would be a return to form. I was wrong.

    The multiplayer military FPS market is dominated by two forces: Activision's Call of Duty (COD) series and EA's Battlefield. Fans of each franchise are loyal to the point of zealotry with little crossover between player bases. Here's where I stand: COD jumped the shark with Modern Warfare 2 in 2009. It's flip-flopped from WW2 to present-day combat and back again, tried sci-fi, and even the Battle Royale trend with the free-to-play Call of Duty: Warzone (2020), which has been thoroughly ruined by hackers and developer inaction.

    Continue reading
  • American diplomats' iPhones reportedly compromised by NSO Group intrusion software

    Reuters claims nine State Department employees outside the US had their devices hacked

    The Apple iPhones of at least nine US State Department officials were compromised by an unidentified entity using NSO Group's Pegasus spyware, according to a report published Friday by Reuters.

    NSO Group in an email to The Register said it has blocked an unnamed customers' access to its system upon receiving an inquiry about the incident but has yet to confirm whether its software was involved.

    "Once the inquiry was received, and before any investigation under our compliance policy, we have decided to immediately terminate relevant customers’ access to the system, due to the severity of the allegations," an NSO spokesperson told The Register in an email. "To this point, we haven’t received any information nor the phone numbers, nor any indication that NSO’s tools were used in this case."

    Continue reading

Biting the hand that feeds IT © 1998–2021